Diphenhydramine is a first-generation ethanolamine-derivative antihistamine, which is the scientific way of classifying antihistamines that can cross the blood-brain barrier – making them very effective but also increasing risks of adverse side effects. What Is Benadryl?īenadryl is the brand name for the active ingredient diphenhydramine HCl. While you should always consult with your veterinarian before giving your dog a human medication, here is what you need to know about using Benadryl for dogs. Veterinarians use diphenhydramine, commonly known by the brand name Benadryl, for dogs on a regular basis to treat allergies, travel anxiety, and motion sickness. However, some human medications are safe for use with dogs, as long as they are used appropriately. Humans and dogs react very differently to medications, which is why veterinarians caution dog owners against making independent decisions about how to medicate their animals. Boxers, sighthounds, and some herding breed dogs can be particularly sensitive to acepromazine.The temptation to reach into our medicine cabinets to treat our pets can be dangerous. In most dogs, the effect lasts for three to four hours. ![]() It is recommended less often because of its side effects: moderate sedation and a decrease in blood pressure. Acepromazine, or “ace,” is more commonly known as a tranquilizing/sedating drug, but it has anti-vomiting effects.Cerenia can be administered safely to dogs who are at least 16 weeks old. It should be given two hours prior to travel on empty stomach, is effective for 24 hours, but should not be used for more than two days in a row for motion sickness. Cerenia (maropitant) acts on a trigger zone in the brain to prevent vomiting.Two medications are FDA-approved for motion sickness in dogs. FDA-Approved Medications for Canine Motion Sickness For these reasons, the safest thing to do is discuss what you want to do with your veterinarian, who may recommend you consider an FDA-approved medication instead. These medicines come in different strengths, which is extremely important for dosages. In addition, some dogs with health issues like kidney, liver, or heart disease might not be good candidates. The main side effect of these antihistamines is mild sedation, but other side effects like diarrhea are possible. A Note of Caution: Side Effects of Dramamine for Dogs Given on an empty stomach, the anti-nausea effect lasts for 24 hours. Dramamine can be given 30 minutes prior to travel, and the anti-nausea effect lasts for three to six hours.īonine (meclizine), also an antihistamine, can be given one to two hours prior to travel. ![]() ![]() Dramamine (dimenhydrinate) is related to Benadryl (diphenhydramine), which you may have administered to your dog if he had a reaction to a bee sting. Some over-the-counter human medication antihistamines, like Dramamine, are widely considered safe for dogs. This alone might not keep your dog from feeling sick, but it will reduce the amount of mess that needs to be cleaned up afterward. To combat motion sickness naturally, it is generally recommended not to feed your dog or puppy within two hours of travel if he often gets motion sickness.
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